How Mood Affects Immunity


We are slowly beginning to unravel the complex interactions between mental and physical health. Researchers have found a wealth of evidence that positive emotions can enhance the immune system, while negative emotions can suppress it. For example, individuals can take up to a year to recover a healthy immune system following the death of their spouse, and long-term caregivers have suppressed immune systems compared with persons in the general population.

Studies on survivors of sexual abuse and those with post-traumatic stress disorder suggest they have elevated levels of stress hormones, as do students at exam time. In these groups of people and others experiencing loneliness, anger, trauma and relationship problems, and infections last longer and wounds take longer to heal. However, having fun with friends and family seems to have the opposite effect on our immune systems. Social contact and laughter have a measurable effect for several hours. Relaxation through massage or listening to music also reduces stress hormones.

The reasons for this link remain unclear, but the brain appears to have a direct effect on stress hormones such as adrenaline and cortisol, which have wide-ranging effects on the nervous and immune systems. In the short term, they benefit us with heightened awareness and increased energy, but when prolonged, the effects are less helpful. They lead to a profound change in the immune system, making us more likely to pick up a bug.

Stress can also over activate the immune system, resulting in an increased risk of autoimmune diseases such as arthritis and multiple sclerosis. Skin conditions such as psoriasis, eczema, hives and acne also may worsen, and stress can trigger asthma attacks.

The mechanisms behind this are complex and still only partially understood, but what we do know is that our reactions to life events can have far-reaching effects on our health. This can work to our advantage — feelings of relaxation reduce cortisol, together with other beneficial bodily responses. In turn, these changes feed into the immune system, making it function well. This happens spontaneously in our daily lives, but we also can encourage it by choosing to look after ourselves.

Insights from the ‘Placebo Effect’

A mind-body link also is found in experiments where people with infections are given placebo (inactive) treatments, which they think are the real thing. Even though the treatment has no medicinal effect, these volunteers report milder symptoms than those given no treatment.

The link also can work the other way once we have developed an infection. Volunteers who are given a symptomless infection feel more anxious and depressed for the next few hours than healthy volunteers. The infection also has a detrimental effect on their memory, lasting several hours.

It’s also been found that happier people may be less likely to come down with colds.

Dr. Sheldon Cohen, professor of psychology at Carnegie Mellon University, Pittsburgh, suggests in his research that our susceptibility to infection can easily be altered by our lifestyle choices.

“Don’t smoke, exercise regularly, eat a healthy diet, try to reduce the stress in your life, and strengthen your interpersonal relationships,” he advises.

Being depressed or anxious is linked to catching more infections and experiencing the symptoms more strongly. Of course, it’s possible that happier people might have a tendency to play down how bad they are actually feeling.

Helping Ourselves

While no one knows for sure how our feelings can affect the immune system, most doctors agree that reducing stress is a good idea. Many stresses cannot be avoided altogether, but we can minimize our ‘background’ stress and our reactions to stressful events.

This is easier said than done. The modern world almost is set up to produce anxiety and frustration. But we can manage stress by reducing the demands upon us, increasing our ability to cope with them, or both.

Creative thinking may lead you to ways — such as delegating work or deleting less important items from your to-do lists — to help reduce stress. Then you can look for ways to improve your coping ability, such as learning a new, useful skill or spending more time unwinding each day. If you are anxiety-prone, consider meditation, yoga, or tai chi classes.

Article: by Jane Collingwood

7 thoughts on “How Mood Affects Immunity

  1. kenny2dogs

    So it’s all psychosomatic, mind over matter is it ? well that’s all right then ! I just “think” I have had a headache for the past 3 month .
    Be well Kate…keep smiling 🙂

  2. RitaElizabeth

    Nice post, Kate! Since I’m a caregiver to my dear husband (he’s doing quite well now, under the circumstances and for his diagnosis), your post hit home.

    Actually, I’ve been working since his diagnosis (two years ago) to simplify our life and set things up for relaxation for him and me. The only trouble is that this has involved the sale of our home, a remodel of the one we’re moving into, combined with dealing with his medical treatments and side effects. I consider all of this as having the goal of stress reduction, even though the process has led to increased stress.

    Our home is sold now, our remodel is almost complete, and my husband’s medical treatments have been efficacious. Soon we’ll be moving (yet another stressor), but I am beginning to see a sliver of light at the end of the tunnel. The stress level is going down.

    I do have to say trying to fit in exercise and good diet, and even blogging and chatting with my blogging buddies, reduces my stress. Your post validates what I’ve been trying to do and encourages me. Thanks, Kate (and sorry for the long comment )

    1. Coffee With Kate Post author

      You are most welcome Rita, let your comments flow. When posting this blog I had you and your current circumstances in mind, however three is a message in this blog for all of us.
      Take care and breathe deeply.

  3. Pingback: What Do We Know « The Epigenetics Project Blog

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